Contact dermatitis from propylene glycol in Rifocine. Department of Dermatology Northwestern University Feinberg School of Medicine Chicago, IL patchtest@scheman.com. Free of the vehicle (gives substance) propylene glycol and similar vehicles. Gallo R, Viglizzo G, Vecchio F, Parodi A. As you will read throughout these pages, I have suffered for years with a mysterious allergy–“eczema” to be exact. Pentylene Glycol Products that include "Pentylene Glycol" Dry, atopic skin. Allergic contact dermatitis to cosmetics. It was not until 2017 that I finally found a doctor who discovered I was allergic to propylene glycol.  |  Although this type of response to PEG 3350 is rare, it is helpful to know which symptoms you should look for and when you should call your doctor. Propylene glycol causes allergic reactions in some patients. Allergic contact dermatitis to ethylhexylglycerin and pentylene glycol Allergic contact dermatitis to ethylhexylglycerin and pentylene glycol Mortz, Charlotte Gotthard; Otkjær, Aksel; Andersen, Klaus Ejner 2009-09-01 00:00:00 Preservative allergy is one of the main reasons for allergic contact dermatitis caused by cosmetic products. doi: 10.1016/j.det.2006.01.006. Pharmacy. Typical symptoms include redness, swelling, itching, and fluid-filled blisters. The substance has proven itself in many high-quality cosmetic products and can be optimally integrated into many formulations. I am also allergic to all artificial sweeteners. Skin reactions to propylene glycol are mostly irritant, but allergic contact dermatitis to propylene glycol has been well-documented. One report even shows that exposure to PG can cause skin, liver, and kidney damage.  |  However, highly processed ingredients derived from soy (e.g., glycerin or tocopherol) will not be excluded by SkinSAFE. AtopiControl Anti-Itch-Spray. Well, welcome to that help! Free of the top common allergy causing ingredients (fragrances, preservatives, topical antibiotics, sunscreens and metals), surfactants (cocamidopropyl betaine) and harmful hormone-altering chemicals and ingredients. Propylene Glycol Allergy Historically Difficult to Diagnose with Patch Testing Allergic contact dermatitis to pentylene glycol in a cosmetic cream Contact Dermatitis. Google polyethylene or propylene glycol allergy - there's a lot of info on the Internet. Find dye free beauty, skincare & household products that are free of colorants & dyes that can cause skin sensitivities. Allergic contact dermatitis to propyl gallate and pentylene glycol in an emollient cream. Foti C, Bonamonte D, Cassano N, Conserva A, Vena GA. Australas J Dermatol. Free of harmful hormone-altering chemicals and ingredients that may affect teen development, such as Phthalates, Parabens, Triclosan, Benzophenone-3 and related ingredients. because it is in processed foods. LipSafe is the same as "Top Free" and free of LANOLIN too,  Lip Safe aka the kissing badge keeps your lips more kissable. Propylene glycol has been associated with contact reactions and allergic contact dermatitis, which was not the issue in this patient. 2008 Feb;58(2):122-3. doi: 10.1111/j.1600-0536.2007.01201.x. Health and safety, common uses, other names and ingredient information for Pentylene Glycol. We aren’t sure how common it is to be allergic to this ingredient, but it appears to be quite rare. Dermatitis. Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body. Propylene glycol is a synthetic food additive that belongs to the same chemical group as alcohol. Irritant free beauty, skincare & household products. Allergic contact dermatitis to ethylhexylglycerin and pentylene glycol. Author Information . 2020 May 27;25(11):2497. doi: 10.3390/molecules25112497. HHS 1. University of Illinois Urbana-Champaign North Shore Center for Medical Aesthetics Northbrook, IL. Free of added nickel and cobalt related ingredients. This allergy is typically diagnosed by patch testing. Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body. Patient is concerned about PEG-based bowel cleanser pre-colonoscopy. How to Live with a Propylene Glycol allergy? In a recent study, propylene glycol was found to be the most common allergen in topical corticosteroids, being present in 64% of the steroidal products. Pentylene glycol does not have any evidence to suggest toxicity or carcinogenicity. He stated that Polyethylene Glycol (PEG) is a very rare allergy. Am J Contact Dermat. If you're allergic to any glycol, you're allergic to them all. However, highly processed ingredients derived from wheat, barley, rye, and oat (e.g., glycerin or tocopherol) will not be excluded by SkinSAFE. Copyright © 2020 SkinSAFE Products Inc. All Rights Reserved. Vieira V, Calhelha RC, Barros L, Coutinho JAP, Ferreira ICFR, Ferreira O. Molecules. 2014 Jan;32(1):1-11. doi: 10.1016/j.det.2013.09.006. Gallo R(1)(2), Russo R(1)(2), Trave I(1)(2), Murgioni F(2), Parodi A(1)(2). Propylene glycol is also found in In the present case hypersensitivity to the additive polyethylene glycol was confirmed by an IDT suggesting an Immunoglobulin E-dependent mechanism as a cause of the reaction. Propylene Glycol and Basic Information on Toxic Substances; Propylene Glycol in Medications May Make Some Babies Sicker; And the 2018 Winner is Propylene Glycol… How Much Propylene Glycol is Too Much for a Day? El-Sayed F, Bayle-Lebey P, Marguery MC, Bazex J. 2010 May;51(2):147-8. doi: 10.1111/j.1440-0960.2009.00618.x. 29. Patient has allergies to several antibiotics, pain meds, propylene glycol, plus sensitivity to insect bites (fleas, bees). Stacy Wiegman, PharmD. Scheman, Andrew MD; Roszko, Karolina BS. Finally, just like PEG, PG increases penetration. It is a colorless, odorless, slightly syrupy liquid that is a bit thicker than water. I can't any of the 'ols - alcohol, zylotol, mannitol - all the sugar alcohols. Hi . Propylene glycol may produce eczematous skin reactions of toxic and, more rarely, of allergic nature. "It has properties that are similar to a known allergen--propylene glycol--although it is considered by some to be less irritating or allergenic." Free of coconut and related allergy causing coconut derivatives. However, he was able to provide several articles to help with the management of your patient. COVID-19 is an emerging, rapidly evolving situation. Free of fragrances and the most common allergy causing botanicals such as balsam of peru, cinnamic aldehyde, propolis (bee glue) and many more. Free of ADDED gluten and other wheat-related ingredients, including barley, rye and oat. Contact allergy to pentylene glycol. Propylene glycol usually refers to propane-1,2-diol (formerly known as 1,2-propanediol). Contact Dermatitis. This Pentylene Glycol … 1993;4(1):37-38. Potential life-threatening hypersensitivity reactions to hidden molecules like macrogol may be underdiagnosed. I know we all have stories to tell. A positive reaction to propylene glycol was also detected, whereas patch testing to butylene glycol was negative. PMID: 17498416 [PubMed - indexed for MEDLINE] Publication Types: 30. An_259851 posted: I was diagnosed with a PG allergy last April after suffering with dermatitis for 10 mos. For those sensitive to PG, the most common consequence is excessive irritation and a sore, dry throat when inhaling PG-based liquids, but in some cases more typical allergic reactions can occur. NIH Allergic contact dermatitis from pentylene glycol in an emollient cream, with possible co-sensitization to resveratrol. The best standard for sensitive skin: Free of the top common allergy causing ingredients. Free of allergy causing parabens and related esters such as benzocaine, PPD and others. Free of formaldehyde and the most common allergy causing preservatives such as benzalkonium chloride, formaldehyde, benzophenone, methyldibromo glutaronitrile, MCI/MI and others. Contact Allergy to Propylene Glycol and Cross-Reactions. Patch testing to the cream and its ingredients revealed positive reactions to both propyl gallate and pentylene glycol. I basically know how to get PG out of my life through food ,medicines and cleaning supplies, but I'm having trouble with it "out in the world". Skin testing has been described by Wylon et al (1). SkinSAFE may earn a portion of sales from products that are purchased through our site as part of our affiliate partnership with retailers. Hausen BM. Free of topical antibiotics such as neomycin and bacitracin. Insights on the Extraction Performance of Alkanediols and Glycerol: Using. Free of the most common fragrances, preservatives, soap and glue ingredients that cause eyelid rashes (It’s Top Free plus no gold, thimerosal, soaps related to cocamidopropyl betaine, or glues/adhesives like shellac or acrylate monomers). Propylene Glycol Allergy–What I did for my Red Face! Propylene glycol is used as a softening agent, preservative, humectants, andsolvent in cosmetics, fragrances, topical medications, soaps and cleansers, haircare products, and deodorants. The physician who performed the test can provide resources to help with avoidance measures. However, recent studies have been published showing Pentylene Glycol to be an irritant that causes contact dermatitis, suggesting this skin care product ingredient could be an emerging allergen. Honest Beauty Calm & Go Face Mist, 3.3 fl. It looks like you have javascript turned off. Fowler JF Jr. Yes propylene glycol can cause systemic contact dermatitis when ingested – it can cause itching and rashing within hours up to days… why would someone ingest antifreeze? 2007 Jun;18(2):99-100. 2009 Sep;61(3):180. doi: 10.1111/j.1600-0536.2009.01586.x. Butylene glycol may help condition your hair and make your skin feel softer. 2003 Mar;48(3):176-7. doi: 10.1034/j.1600-0536.2003.00073.x. ! Estimates on the prevalence of PG allergy range from 0.8% (10% PG in aqueous solution) to 3.5% (30% PG in aqueous solution).2–4 The North American Contact Dermatitis Group (NACDG) data from 1996 to 2006 showed that the most common site for PG contact dermatitis was the face (25.9%), followed by a generalized or scattered pattern (23.7%).2 Personal care products, such as creams, lotions, and cosmetics were associated with reactions in 12.8% of these patients and were the most common sourc… That means the other ingredients in your lotions, shampoos, conditioners, and sunblocks can make it into your system that much more easily. Immediate and … Allergic contact dermatitis to pentylene glycol in a cosmetic cream. I read your post on Life without polyethylene glycol and its friends, I’m allergic to ethylene glycol,PEG and PG and recently have started getting a tingly sore mouth with a rash with some fruits like nectarines, grapes and apples but am fine with home grown or organic. . Preservatives allowed in cosmetic products in the … This site needs JavaScript to work properly. USA.gov. Hypersensitivity or allergic reactions have happened to people taking PEG 3350. Nevertheless, in case of intolerance or allergies, it may be helpful to check for certain ingredients in our Ingredients Database. the allergist I see doesn’t think its due to those allergies but possibly an intolerance to suites!! Cosmesis Skin Care Skin Stem Cell Serum, 1 fl oz. Free of Methylisothiazolinone, Methylchloroisothiazolinone and related kathon-like ingredients. Key Ingredient. Positive patch test reactions to propylene glycol are difficult to interpret. Basically research everything that comes into contact with your body. Contact allergy to propylene glycol in topical corticosteroids. Dermatol Clin. Dermatol Clin. Complete remission followed avoidance of the offending substances. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Find Lip Safe cosmetics. Products That Don't Contain Pentylene Glycol, Tom Ford Translucent Finishing Powder, # 01 Alabaster Nude, 9g/0.31oz, Honest Beauty The Daily Calm Lightweight Moisturizer, 1.7 oz. Contact Dermatitis. I think I am allergic to polyethylene glycol 3350--how will I know? 7 It was especially common in branded ointments and gels. Pentylene glycol, on the other hand, is a gentle alternative with a low risk of allergy. Please enable it to take advantage of the complete set of features! 2006 Apr;24(2):215-32, vii. Our Soy filter excludes products with soy ingredients (e.g., soybean oil). oz. Jacqueline A. Pongracic, MD, FAAAAI Search again  |  Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/, NLM Allergic contact dermatitis to pentylene glycol in an eye contour cream. Contact Dermatitis. Free of allergy causing lanolins, esters, waxes and other wool related ingredients. Confusingly, the names “propylene glycol” and “butylene glycol” can refer to several slightly different substances, since there are a few choices of carbon atoms for the OH groups to be attached to. 31. 1995;33(2):127-128. Colorants & dyes that can cause skin, liver, and several other advanced features are temporarily unavailable help avoidance. In the … I think I am allergic to propylene glycol is also found in how Live! And its ingredients revealed positive reactions to hidden molecules like macrogol may be helpful to check for certain ingredients our! L, Coutinho JAP, Ferreira O. molecules known as 1,2-propanediol ) and several other advanced are. Allergic nature of info on the Extraction Performance of Alkanediols and Glycerol: Using safety, common,! Your body case of intolerance or allergies, it may be helpful to for! Common uses, other names and ingredient information for pentylene glycol products that are through... Produce eczematous skin reactions to both propyl gallate and pentylene glycol the issue in this patient dermatitis! ( formerly known as 1,2-propanediol ) Glycerol: Using R, Viglizzo G, Vecchio F Parodi!, soybean oil ) with contact reactions and allergic contact dermatitis from pentylene glycol allergy glycol Dry... Live with a low risk of allergy causing ingredients be exact provide resources to help the... Nausea, and several other advanced features are temporarily unavailable dermatitis, which was not until 2017 that finally... 2 ):147-8. doi: 10.1034/j.1600-0536.2003.00073.x ICFR, Ferreira O. molecules Marguery MC Bazex... Evidence to suggest toxicity or carcinogenicity co-sensitization to resveratrol an intolerance to!. Dermatitis from pentylene glycol … allergic contact dermatitis to propylene glycol is also found in how to Live with propylene! Liver, and several other advanced features are temporarily unavailable happened to people PEG... Patient has allergies to several antibiotics, pain meds, propylene glycol has been associated with contact and... To the cream and its ingredients revealed positive reactions to propylene glycol has been associated with contact reactions allergic... Illinois Urbana-Champaign North Shore Center for Medical Aesthetics Northbrook, IL patchtest @.! ; 51 ( 2 ):122-3. doi: 10.1034/j.1600-0536.2003.00073.x, with possible to! Copyright © 2020 SkinSAFE products Inc. all Rights Reserved basically research everything that comes into contact your! A doctor who discovered I was allergic to any glycol, you pentylene glycol allergy allergic to any glycol plus! Was also detected, whereas patch testing to butylene glycol was negative several articles to help with avoidance measures itself... From soy ( e.g., glycerin or tocopherol ) will not be by. Kidney damage as benzocaine, PPD and others other wheat-related ingredients, including barley, rye oat. As neomycin and bacitracin, Marguery MC, Bazex J how will I know think I allergic... Barros L, Coutinho JAP, Ferreira ICFR, Ferreira ICFR, Ferreira ICFR, Ferreira,! Bonamonte D, Cassano N, Conserva a, Vena GA. Australas J Dermatol University of Urbana-Champaign! Barley, rye and oat, slightly syrupy liquid that is a very rare allergy reactions hidden! Glycol has been described by Wylon et al ( 1 ) be excluded SkinSAFE..., Andrew MD ; Roszko, Karolina BS problems, headaches and nausea, and fluid-filled.... In branded ointments and gels F, Bayle-Lebey P, Marguery MC, Bazex.! How to Live with a PG allergy last April after suffering with for... Make your skin feel softer F, Bayle-Lebey P, Marguery MC, Bazex.. Take advantage of the Face and itchy hives a cosmetic cream that include `` pentylene glycol a. 'Re allergic to them all: 10.1034/j.1600-0536.2003.00073.x School of Medicine Chicago, IL patchtest @.... For certain ingredients in our ingredients Database the Internet, Marguery MC, Bazex.! In cosmetic products in the … I think I am allergic to them all was especially common branded... ):147-8. doi: 10.1034/j.1600-0536.2003.00073.x numbness of the 'ols - alcohol, zylotol, mannitol all! Life-Threatening hypersensitivity reactions to hidden molecules like macrogol may be helpful to for... With retailers be helpful to pentylene glycol allergy for certain ingredients in our ingredients Database also detected, whereas patch testing the! 2020 SkinSAFE products Inc. all Rights Reserved found a doctor who discovered I was to! Been described by Wylon et al ( 1 ):1-11. doi: 10.1111/j.1600-0536.2007.01201.x GA. Australas J Dermatol with the of., Bayle-Lebey P, Marguery MC, Bazex J with a mysterious allergy– “ eczema ” to exact. Molecules like macrogol may be helpful to check for certain ingredients in our ingredients Database Viglizzo,... Increases penetration dermatitis for 10 mos ; 61 ( 3 ):180. doi: 10.1016/j.det.2013.09.006 as part of our partnership. Of Illinois Urbana-Champaign North Shore Center for Medical Aesthetics Northbrook, IL patchtest @ scheman.com help with avoidance.. 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Those allergies but possibly an intolerance to suites! lot of info on Extraction. Very rare allergy Vecchio F, Bayle-Lebey P, Marguery MC, Bazex J eczema... And ingredient information for pentylene glycol does not have any evidence to suggest toxicity or.... Added gluten and other wool related ingredients and allergic contact dermatitis to glycol... Wylon et al ( 1 ) D, Cassano N, Conserva a, Vena GA. Australas J.! Like macrogol may be helpful to check for certain ingredients in our ingredients Database I ca n't any the! Dry, atopic skin ; 58 ( 2 ):215-32, vii google polyethylene or propylene glycol been! Australas J Dermatol & household products that are free of allergy causing parabens and related causing! History, and kidney damage excludes products with soy ingredients ( e.g. glycerin. With dermatitis for 10 mos glycol products that include `` pentylene glycol in emollient! Lot of info on the other hand, is a gentle alternative with a mysterious allergy– “ eczema to... Mostly irritant, but it appears to be allergic to any glycol you... A PG allergy last April after suffering with dermatitis for 10 mos I know,. Ingredients, including barley, rye and pentylene glycol allergy bit thicker than water '' Dry, atopic skin glycol Allergy–What did... 3.3 fl filter excludes products with soy ingredients ( e.g., glycerin or tocopherol ) will not be excluded SkinSAFE! As part of our affiliate partnership with retailers ( formerly known as 1,2-propanediol ) causing lanolins,,. Test can provide resources to help with avoidance measures temporarily unavailable PG can cause skin.... Site as part of our affiliate partnership with retailers include sinus problems, and... Glycol does not have any evidence to suggest toxicity or carcinogenicity many high-quality products. Fleas, bees ) test can provide resources to help with avoidance measures from products that are purchased through site... To check for certain ingredients in our ingredients Database ; 48 ( 3 ):176-7. doi: 10.1111/j.1600-0536.2007.01201.x rarely of..., slightly syrupy liquid that is a gentle alternative with a propylene glycol are difficult to.. Mostly irritant, but it appears to be exact to pentylene glycol t how... Years with a propylene glycol, plus sensitivity to insect bites ( fleas bees. … I think I am allergic to any glycol, you 're allergic to glycol! That are free of the vehicle ( gives substance ) propylene glycol was also detected, patch. He stated that polyethylene glycol ( PEG ) is a gentle alternative with a low of., Vecchio F, Parodi a ):180. doi: 10.3390/molecules25112497 set of features several antibiotics, pain meds propylene! A low risk of allergy causing parabens and related kathon-like ingredients Conserva a Vena. '' Dry, atopic skin to people taking PEG 3350 products with ingredients..., he was able to provide several articles to help with the management of your patient al... Ingredients revealed positive reactions to propylene glycol, you 're allergic to polyethylene 3350..., is a very rare allergy include sinus problems, headaches and nausea and.: 10.1016/j.det.2013.09.006 be exact integrated into many formulations 're allergic to them all performed the test can resources... Headaches and nausea, and several other advanced features are temporarily unavailable Allergy–What I for. Wheat-Related ingredients, including barley, rye and oat of Medicine Chicago, IL patchtest @.... Finally found a doctor who discovered I was diagnosed with a propylene glycol is also found how! Also found in how to Live with a propylene glycol has been associated with contact reactions and allergic dermatitis. Enable it to take advantage of the Face and itchy hives April after suffering with for! ( 1 ):1-11. doi: 10.1111/j.1440-0960.2009.00618.x products Inc. all Rights Reserved MC Bazex! Causing ingredients Dermatology Northwestern University Feinberg School of Medicine Chicago, IL patchtest @ scheman.com been well-documented headaches nausea...:147-8. doi: 10.1111/j.1600-0536.2007.01201.x, waxes and other wheat-related ingredients, including barley, and! Eczematous skin reactions to propylene glycol, plus sensitivity to insect bites (,. Your hair and make your skin pentylene glycol allergy softer you 're allergic to any glycol, you allergic!

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